Esophageal schwannoma

a case series

Authors

DOI:

https://doi.org/10.29327/2396527.65.65-4

Keywords:

Schwannoma, Esophageal Schwannoma, Mesenchymal Tumors of the Gastrointestinal Tract

Abstract

Introduction: Schwannoma is a neoplasm, usually benign, originating from Schwann cells, responsible for the formation of the myelin sheath in peripheral nerves. It is most frequently found in the peripheral and central nervous systems; however, it can rarely arise in the gastrointestinal tract. It presents an intramural location.
Objective: To report a series of cases of Esophageal Schwannoma (ES).
Method: Review of the results of 65,484 upper digestive endoscopy (UDE) exams, performed at a Private Clinic in Goiânia-GO, and their respective biopsies. Results: Of these exams, 12 (0.018%) cases of ES were diagnosed, with a mean age of 43.4 ± 5.2 years, ranging from 17 to 82 years. Eight (66.6%) were female. The most common site of involvement was the distal esophagus (76.9%).
Conclusion: ES is a rare tumor in the digestive tract. In the present study, it was found in 0.018% of UDE exams. We observed a higher prevalence in females (66.6%). The distal esophagus was the most affected segment (76.9%).

References

Kobayashi N, Kikuchi S, Shimao H, Hiki Y, Kakita A, Mitomi H, et al. Benign esophageal schwannoma: report of a case. Surg Today. 2000 Jun;30:526-9.

Miettinen M, Lasota J. Gastrointestinal stromal tumors--definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch. 2001 Jan;438:1-12.

Kitada M, Matsuda Y, Hayashi S, Ishibashi K, Oikawa K, Miyokawa N. Esophageal schwannoma: a case report. World J Surg Oncol. 2013 Oct 2;11:253.

Shelat VG, Li K, Naik S, Ng CY, Rao N, Rao J, et al. Abdominal Schwannomas: case report with literature review. Int Surg. 2013 Jul-Sep;98(3):214-8.

Vila R, Michaelsen M, Bonamigo, K, et al. Gastrointestinal schwannoma: case report. Arq Bras Cir Dig, 2016 Jul-Sep;29(3):211-2.

Kassis ES, Bansal S, Perrino C, Walker JP, Hitchcock C, Ross P Jr, et al. Giant asymptomatic primary esophageal schwannoma. Ann Thorac Surg. 2012 Apr;93(4):e81-e83.

Chen HC, Huang HJ, Wu CY, Lin TS, Fang HY. Esophageal schwannoma with tracheal compression. Thorac Cardiovasc Surg. 2006 Dec;54(8):555-8.

Liu D, Yang Y, Qi Y, Wu K, Zhao S. Schwannoma of the esophagus: a case report. Oncol Lett. 2015 Nov;10(5):3161-2.

Ferrante M, Khan A, Fan C, Jelloul FZ. Schwannoma of the cervical esophagus. Rare Tumors [Internet]. 2014 Jun 25;6(2):5361. doi: 10.4081/ rt.2014.5361

Kozak K, Kowalzyk M, Jesionek-Kupnicka D, Kozak J. Benign intramural schwannoma of the esophagus - case report. Kardiochir Torakochirurgia Pol. 2015 Mar;12(1):69-71.

Peng H, Han L, Tan Y, Chu Y, Lv L, Liu D and Zhu H. Clinicopathological characteristics of gastrointestinal schwannomas: A retrospective analysis of 78 cases. Front. Oncol. 2022, 12:1-8.

Published

2024-04-26

How to Cite

1.
Andrade LC, Silvério NR, Oliveira GRCN, de Oliveira MAR, Silvério A de O. Esophageal schwannoma: a case series. Rev Goiana Med [Internet]. 2024 Apr. 26 [cited 2025 Feb. 23];65(65). Available from: https://amg.org.br/osj/index.php/RGM/article/view/42