Extensive uterine myomatosis in a woman with spinal muscular atrophy

case report

Abstract

Uterine fibroids, the most prevalent benign tumors in the female pelvis and common in women of reproductive age, have variable characteristics and are influenced by hormonal factors, such as estrogen and progesterone. This report describes the case of a 43-year-old female patient with a large uterine fibroid associated with spinal muscular atrophy (SMA) type II. The patient was at high surgical risk due to severe ventilatory disorders and restricted mobility. After diagnosis by pelvic ultrasound, she underwent total abdominal hysterectomy and bilateral salpingectomy. Surgery revealed a myomatous uterus comparable to a 7-month gestation, weighing 1340 g. The anatomopathological examination identified a myometrium with leiomyoma, secretory endometrium and chronic cervicitis, with no signs of malignancy. The study reinforces the relevance of early diagnosis and individualized management of uterine fibroids, especially in cases associated with challenging health conditions such as SMA.