Double dementia
the association between normal pressure hydrocephalus and semantic dementia
Keywords:
Co-pathology, Temporal variant frontotemporal dementia, Semantic dementia, Frontotemporal lobar degeneration, Idiopathic normal pressure hydrocephalusAbstract
Semantic Dementia (SD), which belongs to the group of Frontotemporal Lobar Degenerations, usually presents in the pre-senile stage, with no well-established risk factors. Normal Pressure Hydrocephalus (NPH) has been associated with neurodegenerative diseases; however, there are no descriptions in the literature regarding the association between SD and NPH. In this report, we present the case of a patient with congenital NPH and moderate intellectual disability who progressed to SD, highlighting the overlap of symptoms from both entities.
References
Caixeta L, Mansur LL. Demência semântica: avaliação clínica e de neuroimagem. Arq Neuropsiquiatr [Internet]. 2005 Jun [Cited 2024 Nov 8];63(2a):348-51. Available from: https://www.scielo.br/j/anp/a/LTKFQT8fK7jzzD74RYvGvng/ doi: 10.1590/S0004-282X2005000200030
Snowden JS, Goulding PJ, Neary D. Semantic dementia: a form of circumscribed atrophy. Behav Neurol [Internet]. 1989 [Cited 2024 Nov 8];2:167-82. Available from: https://onlinelibrary.wiley.com/doi/10.1155/1989/124043 doi: 10.1155/1989/124043
Belliard S, Merck C, Jonin PY, Vérin M. Semantic dementia: aspects of the early diagnosis. Revue Neurologique [Internet]. 2013 Oct [Cited 2024 Nov 8];169(10):806-10. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0035378713008655 doi: 10.1016/j.neurol.2013.07.007
Malm J, Graff-Radford NR, Ishikawa M, Kristensen B, Leinonen V, Mori E, Owler BK, Tullberg M, Williams MA, Relkin NR. Influence of comorbidities in idiopathic normal pressure hydrocephalus - research and clinical care. a report of the ISHCSF task force on comorbidities in INPH. Fluids Barriers CNS [Internet]. 2013 Jun 10 [Cited 2024 Nov 8];10(1):22. Available from: https://fluidsbarrierscns.biomedcentral.com/ articles/10.1186/2045-8118-10-22 doi: 10.1186/2045-8118-10-22
Williams MA, Relkin NR. Diagnosis and management of idiopathic normal-pressure hydrocephalus. Neurol Clin Pract [Internet]. 2013 Oct 3 [Cited 2024 Nov 8];3(5):375-85. Available from: https://www.neurology.org/doi/10.1212/CPJ.0b013e3182a78f6b doi: 10.1212/CPJ.0b013e3182a78f6b
Korhonen VE, Solje E, Suhonen NM, Rauramaa T, Vanninen R, Remes AM, Leinonen V. Frontotemporal dementia as a comorbidity to idiopathic normal pressure hydrocephalus (iNPH): a short review of literature and an unusual case. Fluids Barriers CNS [Internet]. 2017 Apr 19 [Cited 2024 Nov 4];14:10. Available from: https://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-017-0060-7 doi: 10.1186/s12987-017- 0060-7
Guilhem de Lataillade A, Boutoleau-Bretonnière C, Aguilar-Garcia J, Pallardy A, Bigot-Corbel E, Roualdes V, Leroy J, Damier P, Pouclet-Courtemanche H. Idiopathic normal pressure hydrocephalus and frontotemporal dementia: an unexpected association. Brain Commun [Internet]. 2022 Dec 14 [Cited 2024 Nov 8];4(6):fcac319. Available from: https://academic.oup.com/braincomms/article/4/6/fcac319/6895872 doi: 10.1093/braincomms/fcac319
Korhonen VE, Remes AM, Helisalmi S, Rauramaa T, Sutela A, Vanninen R, Suhonen NM, Haapasalo A, Hiltunen M, Jääskeläinen JE, Soininen H, Koivisto AM, Leinonen V. Prevalence of C9ORF72 expansion in a large series of patients with idiopathic normal-pressure hydrocephalus. Dement Geriatr Cogn Disord [Internet]. 2019 [Cited 2024 Nov 8];47(1-2):91-103. Available from: https://karger.com/dem/article-abstract/47/1-2/91/103387/Prevalence-of-C9ORF72-Expansion-in-a-Large-Series doi: 10.1159/000497306
